Abstract
In order to enable local functionalisation of label-free optical waveguide biosensors in a cost effective mass-fabrication compatible manner, we investigate surface modification employing inkjet printing of a) functional polymers (biotin-modified polyethyleneimine (PEI-B)) to implement high receptor densities at the surface and b) UV-curable benzophenone dextran (benzo-dextran) to form a voluminous porous hydrogel matrix. The combination of these approaches on a single chip is promising for the detection of biomolecules. We evaluate these functional polymers and hydrogels on an integrated four-channel silicon nitride (Si3N4) waveguide based Mach-Zehnder interferometric (MZI) sensor platform operating at a wavelength of 850nm (TM-Mode). © 2016 The Authors. Published by Elsevier Ltd.
Original language | English |
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Pages | 337-340 |
DOIs | |
Publication status | Published - 2016 |
Externally published | Yes |
Keywords
- Cost effectiveness
- Curing
- Dextran
- Functional polymers
- Hydrogels
- Ink jet printing
- Polymers
- Printing
- Silicon nitride
- Waveguides
- Cost effective
- Detection of biomolecules
- Functionalisation
- Ink-jet printing technologies
- Mach-Zehnder
- Polyethyleneimine
- Porous hydrogels
- Sensor platform
- Surface treatment